Solution Formulation Development of a VEGF Inhibitor for Intravitreal Injection
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چکیده
منابع مشابه
A calipers-free intravitreal anti-VEGF injection technique.
Dear Editor, Intravitreal injection of drugs such as anti-vascular endothelial growth factor (anti-VEGF) agents and corticosteroids has shown encouraging results in the treatment of many ocular diseases. In developed countries, this type of injection is probably the most frequently performed vitreoretinal procedure. However, it has the potential for serious complications, such as endophthalmiti...
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Stability ofMelphalan Solution for Intravitreal Injection for Retinoblastoma Intravitreal injections for the treatmentof retinoblastomahave been gaining relevance among ophthalmologists, supported by reports on outcome and improvement of the administration technique.1 Currently, doses up to 30 μg per injection are used according to an extensively described technique for intravitreal injection t...
متن کاملDevelopment of a Combined Solution Formulation of Atropine Sulfate and Obidoxime Chloride for Autoinjector and Evaluation of Its Stability
Atropine (AT) and oximes, alone or in combination, have been proven greatly valuable therapeutics in the treatment of organophosphates intoxications. An injectable mixture of AT and obidoxime (OB) was formulated for administration by automatic self-injector. The aqueous single dose solution contained 275 mg obidoxime chloride and 2.5 mg atropine sulfate per 1 ml (220 mg and 2 mg per 0.8 effecti...
متن کاملDevelopment of a Combined Solution Formulation of Atropine Sulfate and Obidoxime Chloride for Autoinjector and Evaluation of Its Stability
Atropine (AT) and oximes, alone or in combination, have been proven greatly valuable therapeutics in the treatment of organophosphates intoxications. An injectable mixture of AT and obidoxime (OB) was formulated for administration by automatic self-injector. The aqueous single dose solution contained 275 mg obidoxime chloride and 2.5 mg atropine sulfate per 1 ml (220 mg and 2 mg per 0.8 effecti...
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ژورنال
عنوان ژورنال: AAPS PharmSciTech
سال: 2011
ISSN: 1530-9932
DOI: 10.1208/s12249-011-9591-4